Are Treatment Effects of ACEI and ARB in Post-MI Patients Homogeneous?
نویسندگان
چکیده
منابع مشابه
Are treatment effects of ACEI and ARB in post-MI patients homogeneous?
he outcome of patients with acute myocardial infarction (MI) has been substantially improved by the introduction of reperfusion therapy and its continuous refinement. Current reperfusion methodology salvages more than 50% of the ischemic myocardium from infarction in approximately half of acute MI patients without cardiogenic shock. 1 However, in 25% of acute MI patients, myocardial salvage by ...
متن کاملDiuretic uptitration with half dose combined ACEI + ARB better decreases proteinuria than combined ACEI + ARB uptitration.
BACKGROUND Residual proteinuria is a strong modifiable risk factor for renal failure progression. We previously showed that the antiproteinuric effect of combined half doses of angiotensin-converting enzyme inhibitor (ACEI) and angiotensin receptor blocker (ARB) is increased by raising diuretic dosage. Methods. We tested whether uptitration of loop diuretics on top of combined half doses of ACE...
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The activation of the renin angiotensin aldosteron (RAA) system plays a major role in the progression of chronic kidney disease (CKD). Inhibition of the RAA system ameliorates renal injury and improves the prognosis of CKD patients (1-3). On the basis of solid evidence from numerous animal model experiments and clinical trials of RAA inhibitors, beyond their action of lowering blood pressure, t...
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Abstract Objectives: Interruption of rennin-angiotensin-aldosterone system has become a leading therapeutic strategy in the treatment of diabetic nephropathy however, ACEIs and ARBs do not uniformly suppress the rennin-angiotensin-aldosterone system. Plasma aldosterone levels are elevated in a group of patients despite therapy and this phenomenon known as aldosterone escape or aldosterone brea...
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ژورنال
عنوان ژورنال: Circulation Journal
سال: 2009
ISSN: 1346-9843,1347-4820
DOI: 10.1253/circj.cj-09-0105